yer man, im running two 12 inch cadience subs, 350 watts each sub, powered by a 1000 watt cadience amp. No problems at all getting the bass through, they hit that hard that ive nocked my numberplate cover off at a little show i was at. I nocked the rear ski pass shelf out aaswell, didnt make that much of a difference, but either way, you can deffinately hear the bass no problems. What are you trying to run in your car?