I have two bags ready. One is an apocalyptic impending nuclear strike bug-out-bag. The other is a Red Dawn/Zombie attack kit.
My BOB has MREs, my old Army uniforms, some warm clothes (gloves, hat, wool socks, etc.), a survival kit, and various other items. I have it sitting with my Battle Kit, and I'd take it all with me.
My Battle Kit is a holster, tactical vest, battle bag and a large Camelbak pack. I have a stash of magazines and ammunition sitting in my safe ready to go at all times, just in case. I also have batteries, lights, tools, a multi tool, and other stuff that I can survive on for a short period of time. In all reality, if a major event occurred, I'd have to go to my work, so I'd just have to make sure I was able to get there.