Depends on how the encounters occurred. If she was in a relationship with each guy then it wouldn't concern me. If there were 10 one nighters, it would be a different story. It would take some investigating and prodding to find out, so it is probably better to just assume the best and forget the past. Unless it starts to burn like fire while urinating.
BTW did you tell her about the time you made out with your sister while wearing a lucha libre mask?